Course Summary
This course covers the principles and methods of molecular evolution and their applications in phylogenetics, population genetics, and comparative genomics.Key Learning Points
- Understand the principles and methods of molecular evolution
- Learn how to apply molecular evolution to phylogenetics, population genetics, and comparative genomics
- Explore current research in molecular evolution
Job Positions & Salaries of people who have taken this course might have
- Bioinformatics Scientist
- USA: $87,000
- India: ₹7,20,000
- Spain: €36,000
- Evolutionary Biologist
- USA: $65,000
- India: ₹5,00,000
- Spain: €26,000
- Geneticist
- USA: $72,000
- India: ₹6,00,000
- Spain: €30,000
Related Topics for further study
Learning Outcomes
- Gain a solid understanding of the principles and methods of molecular evolution
- Learn how to apply molecular evolution in research
- Be prepared to conduct research in molecular evolution
Prerequisites or good to have knowledge before taking this course
- Basic knowledge of genetics and evolution
- Familiarity with programming languages such as Python
Course Difficulty Level
IntermediateCourse Format
- Online self-paced
- Video lectures
- Quizzes and assignments
Similar Courses
- Bioinformatics: Introduction and Methods
- Phylogenetics and Tree Thinking
- Genomic Data Science
Related Education Paths
Notable People in This Field
- John Hawks
- Joe Felsenstein
Related Books
Description
In the previous course in the Specialization, we learned how to compare genes, proteins, and genomes. One way we can use these methods is in order to construct a "Tree of Life" showing how a large collection of related organisms have evolved over time.
Outline
- Week 1: Introduction to Evolutionary Tree Construction
- (Check Out Our Wacky Course Intro Video!)
- The Fastest Outbreak
- Transforming Distance Matrices into Evolutionary Trees
- Toward an Algorithm for Distance-Based Phylogeny Construction
- Additive Phylogeny
- Course Details
- Week 1 Quiz
- Week 2: More Algorithms for Constructing Trees from Distance Matrices
- Using Least Squares to Construct Distance-Based Phylogenies
- Ultrametric Trees
- The Neighbor-Joining Algorithm
- Week 2 Quiz
- Week 3: Constructing Evolutionary Trees from Characters
- Character-Based Tree Reconstruction
- The Small Parsimony Algorithm
- The Large Parsimony Algorithm
- Evolutionary Tree Reconstruction in the Modern Era
- Week 3 Quiz
- Week 4
- Paleontology Meets Computing
- Decoding an Ideal Spectrum
- From Ideal to Real Spectra
- Peptide Sequencing
- Note on This Week's Assignments
- Week 4 Quiz
- Week 5: Resolving the T. rex Peptides Mystery?
- Peptide Identification
- Spectral Dictionaries
- The Ostrich Hemoglobin Riddle
- Searching for Post-Translational Modifications
- Spectral Alignment Algorithm
- Note on This Week's Content
- Week 5 Quiz
- Week 6: Bioinformatics Application Challenge
Summary of User Reviews
Find out what people are saying about the Molecular Evolution course on Coursera. Users have praised the course for its comprehensive coverage of the subject matter. Read on to learn more about the pros and cons of this course.Key Aspect Users Liked About This Course
Comprehensive coverage of the subject matterPros from User Reviews
- Expert instructors with extensive knowledge of molecular evolution
- Course content is well-organized and easy to follow
- Provides a solid foundation for further study in related fields
- Course delivery is engaging and interactive
- Great course for both beginners and advanced learners
Cons from User Reviews
- Some users found the course to be too challenging
- Not enough practical applications of the concepts taught
- More quizzes and assessments would be helpful for better understanding
- Some users found the course to be too theoretical
- Course videos could be shorter to maintain user engagement
Pavel Pevzner
4.6 Raiting
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