Course Summary
This course covers the fundamentals of molecular genetics, including the structure and function of DNA, genetic variation, and gene expression. Students will learn how to analyze and interpret genetic data and apply this knowledge to real-world scenarios.Key Learning Points
- Understand the basics of molecular genetics, including DNA structure and function
- Learn how genetic variation arises and how it can be analyzed
- Explore gene expression and regulation, and how these processes can be studied
Related Topics for further study
Learning Outcomes
- Understand the fundamental concepts of molecular genetics
- Analyze and interpret genetic data
- Apply molecular genetics knowledge to real-world scenarios
Prerequisites or good to have knowledge before taking this course
- Basic knowledge of biology and chemistry
- Familiarity with basic statistical analysis
Course Difficulty Level
IntermediateCourse Format
- Online
- Self-paced
- Video lectures
Similar Courses
- Introduction to Genetics and Evolution
- Molecular Biology
Related Education Paths
Notable People in This Field
- Director of the National Institutes of Health
- Professor of Chemistry and Molecular and Cell Biology
Related Books
Description
You have all heard about the DNA double helix and genes. Many of you know that mutations occur randomly, that the DNA sequence is read by successive groups of three bases (the codons), that many genes encode enzymes, and that gene expression can be regulated.
Outline
- Session 1
- Introduction
- Part 1 - Perspective
- Part 2
- Part 3
- Part 4
- Part 5
- Part 6
- Figures in this module
- Readings (to be read before lectures 4-6)
- Beadle & Tatum
- Session 2
- Part 1
- Part 2
- Part 3
- Part 4
- Part 5
- Part 6
- Part 7 - Quantitative analysis of transformation
- Figures in this module
- Readings (to be read before lectures 4-6)
- Avery Questions
- Session 3
- Part 1
- Part 2
- Part 3
- Part 4
- Figures in this module
- Readings: Read the papers before watching Part 3 & Part 4
- Origin of mutations
- Session 4
- Part 1
- Part 2
- Part 3
- Part 4
- Part 5
- Figures in this module
- Read the papers before watching parts 3 to 5
- DNA structure and the fidelity of replication
- Session 5
- Part 1
- Part 2
- Part 3
- Part 4
- Part 5
- Part 6
- Figures in this module
- Read the 1961 topography paper before watching parts 5 & 6
- Topography and gene fine structure
- Session 6
- Part 1
- Part 2
- Part 3
- Part 4
- Part 5
- Part 6
- Part 7
- Figures in this module
- Read the Champe & Benzer paper before watching Part 2
- Read the Crick paper before watching parts 5 to 7
- Sequence of the end of rIIA and the beginning of rIIB
- The genetic code
- Session 7
- Part 1
- Part 2
- Part 3
- Part 4
- Part 5
- Figures in this module
- Read the Champe & Benzer paper before watching part 2
- Read the Brenner paper before watching parts 3 to 5
- Readings comment on the origin of amber suppressor strains
- Nonsense mutations
- Session 8
- Part 1
- Part 2
- Part 3
- Part 4
- Figures in this module
- Read the Epstein paper before watching part 2
- Read the Edgar & Wood paper before watching parts 3 & 4
- T4 conditional mutants and phage assembly
- Session 9
- Part 1
- Part 2
- Part 3
- Part 4
- Part 5
- Part 6
- Figures in this module
- Read the Tatum and Lederberg paper before watching parts 2 to 4
- Read the Wollman & Jacob paper before watching part 5
- Read the review by Wollman et al. before watching part 6
- Readings
- Recombination and Hfr matings
- Session 10
- Part 1
- Part 2
- Part 3
- Part 4
- Part 5
- Part 6
- Part 7
- Figures in this module
- Read the Pardee et al paper before watching part 5
- Read the Jacob et al short paper before watching part 6
- Read the Jacob and Monod review before watching part 7
- Readings
- The lactose operon
- Session 11
- Part 1
- Part 2
- Part 3
- Part 4
- Figures in this module
- Read the Bertani 1951 paper before watching part 3
- Read the Eisen 1971 paper before watching part 4
- Readings
- The cro gene of phage lambda
- Session 12
- Part 1
- Part 2
- Part 3
- Part 4
- Part 5
- Part 6
- Figures in this module
- Read the Engelsberg et al. paper before watching parts 4 to 6
- Readings
- The arabinose system and positive control
Summary of User Reviews
Discover the world of molecular genetics with this comprehensive course on papers in the field. Users have found this course to be informative and engaging, with a focus on real-world applications of the concepts learned. Many users have praised the course's accessibility and the instructor's expertise.Key Aspect Users Liked About This Course
Real-world applications of molecular genetics conceptsPros from User Reviews
- Instructor is knowledgeable and engaging
- Course content is comprehensive and informative
- Easy to follow lectures and assignments
- Provides a solid foundation for further study in the field
Cons from User Reviews
- Some users found the course to be too basic
- Lack of interaction with other students
- Course material can be dry at times
- Not enough hands-on activities or experiments
Dominique Belin
4.7 Raiting
Classical papers in molecular genetics
- 4.7
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You have all heard about the DNA double helix and genes. These concepts were proposed on the basis of astute genetic experiments, as well as often on biochemical results....
Methods of molecular biology
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The course “Methods of molecular biology” is the first course developed by Al-Farabi Kazakh National University (KazNU) in collaboration and kind support of Peter the Great St....
