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Introduction to High-Throughput Materials Development

Approx. 16 hours to complete

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Course Summary

This course offers an introduction to high-throughput experiments, data analysis, and interpretation. Students will learn how to design experiments, analyze data, and interpret results using various high-throughput technologies.

Key Learning Points

Learn how to design and analyze high-throughput experiments
Understand the principles of data analysis and interpretation
Gain practical experience with various high-throughput technologies

Job Positions & Salaries of people who have taken this course might have

- USA: $98,000
- India: ₹6,50,000
- Spain: €45,000
- USA: $98,000
- India: ₹6,50,000
- Spain: €45,000
- USA: $55,000
- India: ₹3,50,000
- Spain: €28,000
- USA: $98,000
- India: ₹6,50,000
- Spain: €45,000
- USA: $55,000
- India: ₹3,50,000
- Spain: €28,000
- USA: $67,000
- India: ₹4,50,000
- Spain: €32,000

Learning Outcomes

Understand the principles of high-throughput experiments
Gain practical experience with various high-throughput technologies
Learn how to analyze and interpret high-throughput data

Prerequisites or good to have knowledge before taking this course

Basic knowledge of biology and statistics
Access to a computer with internet connection

Course Difficulty Level

Intermediate

Course Format

Online
Self-paced

Similar Courses

Next-Generation Sequencing
Single-Cell RNA Sequencing

Related Education Paths

Notable People in This Field

President and Founding Director of the Broad Institute
Professor of Chemistry and Molecular and Cell Biology

Related Books

Description

This course is an introduction to high-throughput experimental methods that accelerate the discovery and development of new materials.

It is well recognized that the discovery of new materials is the key to solving many technological problems faced by industry and society. These problems include energy production and utilization, carbon capture, tissue engineering, and sustainable materials production, among many others. This course will introduce the learner to a remarkable new approach to materials discovery and characterization: high-throughput materials development (HTMD). Engineers and scientists working in industry, academic or government will benefit from this course by developing an understanding of how to apply one element of HTMD, high-throughput experimental methods, to real-world materials discovery and characterization problems. Internationally leading faculty experts will provide a historical perspective on HTMD, describe preparation of ‘library’ samples that cover hundreds or thousands of compositions, explain techniques for characterizing the library to determine the structure and various properties including optical, electronic, mechanical, chemical, thermal, and others. Case studies in energy, transportation, and biotechnology are provided to illustrate methodologies for metals, ceramics, polymers and composites. The Georgia Tech Institute for Materials (IMat) developed this course in order to introduce a broad audience to the essential elements of the Materials Genome Initiative. Other courses will be offered by Georgia Tech through Coursera to concentrate on integrating (i) high-throughput experimentation with (ii) modeling and simulation and (iii) materials data sciences and informatics. After completing this course, learners will be able to • Identify key events in the development of High-Throughput Materials Development (HTMD) • Communicate the benefits of HTMDwithin your organization. • Explain what is meant by high throughput methods (both computational and experimental), and their merits for materials discovery/development. • Summarize the principles and methods of high throughput creation/processing of material libraries (samples that contain 100s to 1000s of smaller samples). • State the principles and methods for high-throughput characterization of structure. • State the principles and methods for high throughput property measurements. • Identify when high-throughput screening (HTS) will be valuable to a materials discovery effort. • Select an appropriate HTS method for a property measurement of interest. • Identify companies and organizations working in this field and use this knowledge to select appropriate partners for design and implementation of HTS efforts. • Apply principles of experimental design, library synthesis and screening to solve a materials design challenge. • Conceive complete high-throughput strategies to obtain processing-structure-property (PSP) relationships for materials design and discovery.

Outline

Welcome
Target Audience
Course Format and Syllabus
Guest Instructors
Recommended Background
Acknowledgements
Get More from Georgia Tech
Consent Form

Introduction
Introduction
Overview of the MGI Approach and How HTMD Fits
Complexity in Materials Design Part 1
Complexity in Materials Design Part 2
Early History Leading up to HTMD
Recent History of HTMD
Types of High-Throughput Strategies
High-Throughput Computational Screening
Where To Go to Get Started
Early History Leading up to HTMD
Recent History of HTMD
Types of High-Throughput Strategies
Earn a Georgia Tech Badge/Certificate/CEUs
Introduction

Library Preparation
Introduction
Introduction to Experimental Design
Model-Based Experimental Design
Synthesis of Polymers
Polymer Processing Part 1
Polymer Processing Part 2
Additive Manufacturing – Introduction
Metal Alloy Libraries – Introduction Part 1
Metal Alloy Libraries – Introduction Part 2
Vapor Deposition of Thin Films - Introductory Concepts
Vapor Deposition of Thin Films - Making Libraries
Diffusion Multiples
Additive Manufacturing – Metals
Bulk Alloy Libraries - Microstructure Gradients
Microstructure Gradient Alloy Libraries Generated by Non-uniform Heating and Cooling
Microstructure Gradient Alloy Libraries Generated by Non-uniform Deformations
Rapid Alloy Prototyping
Polymer Processing
Additional details on Diffusion Multiples
Jominy End Quench Heat Flow Simulation
Rapid Alloy Prototyping
Library Preparation

High-Throughput Characterization of Composition and Structure
Introduction
Composition and Structure of Polymers
Physical Structure of Polymers
Chemical Structure of Polymers
Composition of Inorganics
Detection of Phase Transformations
Crystal Structure of Inorganics
Composition and Structure of Polymers
In-depth reading on HT methods for inorganic materials
In-depth reading on detection of phase transformations
High-Throughput Characterization of Composition and Structure

High-Throughput Property Measurements
Introduction
Optical Properties
Electrical and Thermal Transport Properties
Introduction
Strength
Instrumented Indentation Test
Measurements using Indentation Methods
Fracture Toughness
Indentation Testing - Polymers and Coatings
Abrasion, Scratch, and Buckling
Catalysis
Sorption, Adsorption & Diffusion
Biological Activity: Cell Culture
Introduction to Corrosion
Corrosion Testing Part 1
Corrosion Testing Part 2
Optical Properties
Electrical and Thermal Transport Properties
Additional details on measuring strength at microscales
Additional details on spherical nanoindentation stress-strain curves
In-depth reading
In-depth reading
Biological Activity: Cell Culture
High-Throughput Property Measurements

Applications
Introduction
Polymers for Proton Exchange Membranes in Fuel Cells – Part 1
Polymers for Proton Exchange Membranes in Fuel Cells – Part 2
Structural Alloys for Energy and Transport - Part 1
Structural Alloys for Energy and Transport - Part 2
Structural Alloys for Energy and Transport - Part 3
Structural Alloys for Energy and Transport - Part 4
Exploration of PSP Linkages in Dual Phase Steel - Introduction
Exploration of PSP Linkages in Dual Phase Steel - Property Measurements
Exploration of PSP linkages in Dual Phase Steel - Microstructure Quantification
Exploration of PSP Linkages in Dual Phase Steel - Property-Structure-Process-Linkages
Exploration of PSP Linkages in Dual Phase Steel - High-throughput Sample Prototyping
Polymers for Proton Exchange Membranes in Fuel Cells
Structural Alloys for Energy and Transport
Take Another Course like this !
Polymers for Proton Exchange Membranes in Fuel Cells
Structural Alloys for Energy and Transport
Exploration of PSP Linkages in Dual Phase Steel

Summary of User Reviews

Pros from User Reviews

In-depth coverage of high-throughput sequencing
Engaging teaching style
Practical exercises help apply knowledge in real-world situations

Cons from User Reviews

Some users found the course too challenging
Limited interaction with instructors
Not suitable for beginners with no prior knowledge of sequencing
Course materials can be overwhelming
Some users found the quizzes too difficult

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