Precision Medicine

  • 3.2
Approx. 29 hours to complete

Course Summary

Precision medicine is an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle. In this course, you will learn about the principles of precision medicine and how it is applied in practice.

Key Learning Points

  • Understand the principles and concepts of precision medicine
  • Learn how precision medicine can be applied in clinical practice
  • Understand the ethical, legal, and social implications of precision medicine

Job Positions & Salaries of people who have taken this course might have

  • Precision Medicine Scientist
    • USA: $99,000
    • India: ₹10,00,000
    • Spain: €47,000
  • Precision Medicine Researcher
    • USA: $80,000
    • India: ₹9,00,000
    • Spain: €38,000
  • Precision Medicine Analyst
    • USA: $70,000
    • India: ₹8,00,000
    • Spain: €32,000

Related Topics for further study


Learning Outcomes

  • Understand the key principles and concepts of precision medicine
  • Be able to apply precision medicine in clinical practice
  • Understand the ethical, legal, and social implications of precision medicine

Prerequisites or good to have knowledge before taking this course

  • Basic understanding of biology and genetics
  • Familiarity with medical terminology

Course Difficulty Level

Intermediate

Course Format

  • Online self-paced
  • Video lectures
  • Quizzes and assessments

Similar Courses

  • Genomic Data Science
  • Introduction to Genetics and Evolution

Related Education Paths


Related Books

Description

This course will provide you with the key knowledge and tools to understand the fundamentals and practical implications of precision medicine, its opportunities and challenges. It will address precision-medicine era diagnostics, treatment selection, genetic counseling, public health interventions, and biomedical research. It will also deal with data science and ethical issues.

Outline

  • Monogenic Diseases
  • Trailer
  • Welcome to the course
  • Introduction to the module
  • Human genome variabilty and phenotype consequences 1
  • Human genome variability and phenotype consequences 2
  • Medical consultation (part 1)
  • Exome sequencing analysis
  • What are the options? discussion between the physician and the biologist
  • Medical consultation (part 2)
  • Rare genetic disorder and precision medicine
  • Ethical, Legal and Social Implications (ELSI)
  • Conclusion
  • How assessments work
  • Syllabus
  • List of Teachers
  • Bibliographic References
  • Human genome variability and phenotype consequences
  • Medical consultation part 1
  • Exome sequencing analysis
  • Rare genetic disorder and precision medicine
  • Ethical, Legal and Social Implications (ELSI)
  • Monogenic disease
  • Complex Diseases
  • Introduction
  • Genetics of complex disorders
  • Environmental determinant
  • Diabetes management today
  • Diabetes risk assessment part 1
  • The key points - answers to the discussion by the expert (part 1)
  • Precision approaches in diabetes
  • Diabetes risk assessment (part 2)
  • The key points - answers to the discussion by the expert (part 2)
  • Conclusion
  • Genetics of complex disorders
  • Environmental determinants
  • How to evaluate the disease risk (part 1)
  • How to evaluate the disease risk (part 2)
  • Complex disease
  • Cancer
  • Somatic mutation theory of cancer
  • Synthetic lethality and oncogene addiction
  • Clinically-orientated analysis
  • Introduction to clinical ethics
  • Objectives of precision oncology
  • Tumor classification
  • What is a biomarker?
  • Somatic bioinformatics pipelines
  • Molecular tumor board
  • Ethical and societal implications
  • Sporadic, familial and hereditary cancer
  • Family history in oncology
  • Genetic counselling in oncology
  • Main hereditary cancer syndromes
  • Case study 1 - part 1
  • Case study 1 - part 2
  • Case study 2 - part 1
  • Case study 2 - part 2
  • Further reading
  • Somatic bioinformatics pipeline
  • Main hereditary cancer syndromes
  • Cancer
  • Health and Prevention
  • Introduction to the module
  • The Revolution of Genetic Technologies
  • Main Opportunities of Genomics
  • Genomics and Complex Chronic Diseases
  • The Revolution of Environmental Technologies
  • Genome-Exposome Interaction
  • Big Data
  • Validity and Massive Information
  • Restitution, Unintended Findings and Actionable Variants
  • Patients' Willingness to Discuss their Genomic Information
  • Evidence-Based Precision Medicine
  • Conclusion
  • New Technologies and Personalized Health: Opportunities and Challenges
  • Tyrell and all.
  • Testing the illustration discussed
  • Testing the understanding of the Tyrell and all. results
  • Big Data
  • Testing challenges of translating genomics into clinical care
  • Health and prevention
  • Pharmacogenomics and Drug Development
  • Introduction to the module
  • Variability in drug response
  • Drug metabolism
  • Role of Transporters in Drug Disposition
  • Case - Pharmacogenomics of Statins
  • Other Cardiovascular Case Studies
  • Pharmacogenomics of opioids
  • Tools for clinicians and patients
  • Current Methods to Identify Pharmacogenomics Variants
  • Phenotyping in the lab
  • Drug development 1
  • Drug development 2
  • Pharmacovigilance
  • Pharmacoeconomics and pharmacogenomics
  • Citizen Centered Consent
  • Data deidentification
  • Conclusion and Future Perspectives
  • Codeine Intoxication Associated with Ultrarapid CYP2D6 Metabolism
  • Table of Pharmacogenetic Associations
  • Case study: antiaggregant and HIV
  • Case Study: the example of oxycodone
  • Variability in drug response
  • Drug metabolism
  • Role of Transporters in Drug Disposition
  • Pharmacogenomics of statins
  • Other cardiovascular diseases
  • Pharmacogenomics of opioids
  • Tools of clinicians and patients
  • Current Methods to Identify Pharmacogenomics Variants
  • Phenotyping in the lab
  • Drug development 1
  • Drug development 2
  • Pharmacovigilance
  • Evaluation of the module
  • Research
  • Introduction to the module
  • First Steps of a Research Project
  • Sample Collection, Biobanking and Data Generation/Recording
  • Data Quality Control and Data Analysis
  • Data dissemination, databases and publication
  • Explanations by the expert
  • Explanation by the expert: patient stratification in traumatic brain injury
  • Explanations by the expert: Steroid Signatures in Toxicology
  • Conclusion of the module
  • Conclusion of the course in Precision Medicine
  • Estimating the causal tissues for complex traits and diseases
  • Abstract section of the article
  • First steps of a research project
  • Sample collection, biobanking and data generation/recording
  • On Data videos above (2)
  • Questions on published article
  • Questions on abstract - please read abstract before answering
  • Patient stratification in traumatic brain surgery
  • Steroid signatures in toxicology
  • Research

Summary of User Reviews

Discover the world of precision medicine and its potential in transforming the future of healthcare with this comprehensive course on Coursera. With a high overall rating, many users praised the course for its engaging content and knowledgeable instructors. One key aspect that stood out for many was the course's emphasis on real-world applications of precision medicine.

Pros from User Reviews

  • Engaging content
  • Knowledgeable instructors
  • In-depth exploration of precision medicine
  • Real-world applications highlighted
  • Interactive learning experience

Cons from User Reviews

  • Some users found the pace too slow
  • Course may be too technical for beginners
  • Limited focus on ethical issues in precision medicine
  • Not enough case studies provided
  • Lack of opportunities for peer-to-peer interaction
English
Available now
Approx. 29 hours to complete
Antoine Geissbuhler, Idris Guessous, Caroline Samer, Christelle Borel, Petros Tsantoulis
University of Geneva
Coursera

Instructor

Antoine Geissbuhler

  • 3.2 Raiting
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