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Non-Alcoholic Fatty Liver Disease – The Essentials

Approx. 18 hours to complete

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Course Summary

This course provides a comprehensive overview of non-alcoholic fatty liver disease (NAFLD) with a focus on the essentials. Students will learn about the epidemiology, pathophysiology, diagnosis, and management of NAFLD.

Key Learning Points

Understand the pathophysiology of NAFLD and its progression to non-alcoholic steatohepatitis (NASH)
Learn about the diagnostic tests and criteria for NAFLD and NASH
Explore the management options for NAFLD and NASH, including lifestyle changes and pharmacotherapy

Learning Outcomes

Understand the pathophysiology of NAFLD and NASH
Identify the diagnostic criteria for NAFLD and NASH
Develop a management plan for patients with NAFLD and NASH

Prerequisites or good to have knowledge before taking this course

Basic knowledge of liver anatomy and physiology
Familiarity with medical terminology

Course Difficulty Level

Intermediate

Course Format

Self-paced
Video lectures
Quizzes

Similar Courses

Liver Diseases: Looking after Your Liver
Gastrointestinal and Liver Disease Nutrition

Related Education Paths

Notable People in This Field

Dr. Ken Fujioka
Dr. Mazen Noureddin

Related Books

Description

Non-Alcoholic Fatty Liver Disease (NAFLD) is a global problem, affecting up to 25% of all individuals. The disease not only increases the risk of liver disease, but also of cardiovascular disease and liver cancer.

During this course, you will learn the essentials of NAFLD. We will begin with an introduction to the physiology of the human liver followed by epidemiology, pathophysiology, clinical medicine, and genetics. Diagnosing NAFLD based on blood tests, diagnostic imaging and histology will be discussed. Complications and treatment options will also be covered in this course including the link between NAFLD and the development of diabetes. Finally, experts will discuss data driven identification of new biomarkers by omics technologies. After completing this course, you will have a broad knowledge about NAFLD ranging from the aetiology and pathophysiology to bedside examinations and treatments.

Knowledge

1) Physiology of the liver and pathophysiological aspects of NAFLD
2) Diagnostics aspects of NAFLD
3) Treatment of NAFLD
4) Complications of NAFLD

Outline

The Liver - Physiology and Disease
The Liver – Our Most Important Organ
Anatomy and Function of the Liver
The Liver and Bile Acids
The Liver Controls Body Metabolism
Introduction to NAFLD
Physiology of the liver
Clinical Practice Guidelines for the management of NAFLD
Week 1

Causes
Epidemiology
Nutrients and Insulin Resistance
Genetics
Fibrosis stage and mortality in NAFLD
Are Lifestyle Therapies Effective for NAFLD Treatment?
Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet
Role of Carbohydrate and Energy Availability
Genetic Aspects of NAFLD
Week 2

Pathophysiological aspects
Pathophysiology
The Multiple-Hit Hypothesis
Impact on Liver Function
The role of macrophages in NAFLD and NASH (abstract only)
NAFLD causes dissociated changes in metabolic liver functions
Week 3

Diagnostics
Diagnostics – The Basic Terms
Blood Tests and Imaging
Histology
Mass-Spectrometry Based Diagnostics and Other Omics Technologies
Mass-Spectrometry Based Proteomics
Interpreting diagnostic accuracy studies for patient care
Noninvasive assessment of liver disease in patients with NAFLD
Design and validation of a histological scoring system for NAFLD
Week 4

Treatment
Life-Style Interventions
Exercise Your Liver
Patient Relevant Outcomes
Pharmacological Treatment
Effects of Moderate and Vigorous Exercise on NAFLD: A Randomized Clinical Trial
Week 5

Complications and Perspective
NASH Cirrhosis
Complications to NASH Cirrhosis
NAFLD and Type 2 Diabetes
What We Learned
CLIF Consortium Acute Decompensation score (Abstract only)
Acute-on-chronic liver failure
NAFLD: a multisystem disease
Week 6

Summary of User Reviews

Discover how to identify, diagnose and treat non-alcoholic fatty liver disease with this informative course from Coursera. Students appreciate the engaging presentation and in-depth knowledge of the instructors.

Key Aspect Users Liked About This Course

The instructors are highly knowledgeable and engaging.

Pros from User Reviews

The course provides a comprehensive overview of non-alcoholic fatty liver disease.
The instructors are highly knowledgeable and engaging.
The course is well-structured and easy to follow.
The course materials are of a high quality.
The course offers practical advice for managing the disease.

Cons from User Reviews

Some students feel that the course is too basic.
The course does not offer much new information for those already familiar with the topic.
Some students find the course too focused on the medical aspects of the disease, without addressing lifestyle factors that contribute to the condition.
The course can be challenging for those without a medical background.
Some students feel that the course lacks practical advice on living with the disease.

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Non-Alcoholic Fatty Liver Disease – The Essentials

Non-Alcoholic Fatty Liver Disease (NAFLD) is a global problem, affecting up to 25% of all individuals. During this course, you will learn the essentials of NAFLD....

Save Course