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Industrial Biotechnology

Approx. 11 hours to complete

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Course Summary

The course is an introduction to industrial biotechnology, covering topics such as microbial genetics, fermentation, and product recovery. It provides an overview of the different steps involved in bringing a biotech product to market, from research and development to commercial production.

Key Learning Points

Learn about the principles of industrial biotechnology and how it is used in various industries
Explore the different stages of biotech product development, from research to commercialization
Understand the role of microbial genetics in biotech production and the use of fermentation for product synthesis

Job Positions & Salaries of people who have taken this course might have

Bioprocess Engineer
- USA: $85,000 - $125,000 per year
- India: ₹5,00,000 - ₹12,00,000 per year
- Spain: €30,000 - €50,000 per year
Research Scientist
- USA: $60,000 - $100,000 per year
- India: ₹3,00,000 - ₹10,00,000 per year
- Spain: €20,000 - €40,000 per year
Quality Control Manager
- USA: $70,000 - $120,000 per year
- India: ₹4,00,000 - ₹12,00,000 per year
- Spain: €25,000 - €45,000 per year

Learning Outcomes

Understand the basic principles of industrial biotechnology
Learn how to apply these principles to different industries
Gain knowledge of the different stages of biotech product development

Prerequisites or good to have knowledge before taking this course

Basic knowledge of biology and chemistry
Familiarity with laboratory techniques

Course Difficulty Level

Intermediate

Course Format

Online
Self-paced

Similar Courses

Biotechnology and Society
Introduction to Biotechnology

Related Education Paths

Notable People in This Field

Professor of Chemistry
Professor of Genetics

Related Books

Description

Fossil fuels have been the primary energy source for society since the Industrial Revolution. They provide the raw material for the manufacture of many everyday products that we take for granted, including pharmaceuticals, food and drink, materials, plastics and personal care.

As the 21st century progresses we need solutions for the manufacture of chemicals that are smarter, more predictable and more sustainable. Industrial biotechnology is changing how we manufacture chemicals and materials, as well as providing us with a source of renewable energy. It is at the core of sustainable manufacturing processes and an attractive alternative to traditional manufacturing technologies to commercially advance and transform priority industrial sectors yielding more and more viable solutions for our environment in the form of new chemicals, new materials and bioenergy. This course will cover the key enabling technologies that underpin biotechnology research including enzyme discovery and engineering, systems and synthetic biology and biochemical and process engineering. Much of this material will be delivered through lectures to ensure that you have a solid foundation in these key areas. We will also consider the wider issues involved in sustainable manufacturing including responsible research innovation and bioethics. In the second part of the course we will look at how these technologies translate into real world applications which benefit society and impact our everyday lives. This will include input from our industry stakeholders and collaborators working in the pharmaceutical, chemicals and biofuels industries. By the end of this course you will be able to: 1. Understand enzymatic function and catalysis. 2. Explain the technologies and methodologies underpinning systems and synthetic biology. 3. Explain the diversity of synthetic biology application and discuss the different ethical and regulatory/governance challenges involved in this research. 4. Understand the principles and role of bioprocessing and biochemical engineering in industrial biotechnology. 5. Have an informed discussion of the key enabling technologies underpinning research in industrial biotechnology 6. Give examples of industrial biotechnology products and processes and their application in healthcare, agriculture, fine chemicals, energy and the environment.

Outline

Enzymes, Enzyme Discovery and Engineering
Welcome to Industrial Biotechnology
Introduction from Nigel Scrutton
Overview and introduction
How do enzymes work?
How do we discover enzymes for application in biotechnology?
How can we study and characterise the catalytic activity of enzymes?
Engineering Enzymes I: Directed Evolution
Engineering Enzymes II: Rational Design of Biocatalysts
Pre Course Survey and Course Credits
Glossary
Enzymes, Enzyme Discovery and Engineering

Methods in Systems and Synthetic Biology
Introduction from Rainer Breiting
Introduction to Synthetic Biology: Visions for Biotechnology 2.0
Designing biological systems: Computational modelling and systems biology
Building biological systems I: Genome synthesis and genome editing
Controlling and engineering pathways in Synthetic Biology
Testing Biological Systems Biological debugging using metabolomics
Deploying biological systems: Perspectives on Responsible Research & Innovation and bioethics I
Deploying biological systems: Perspectives on Responsible Research & Innovation and bioethics II
Conclusions and Outlook Systems and Synthetic Biology
Glossary
Systems and Synthetic Biology
Methods in Systems and Synthetic Biology

Biochemical and Bioprocess Engineering
Introduction from James Winterburn
Introduction from James Lawrence and Michael Sulu
Introduction to Biochemical and Bioprocess Engineering
Microbial fermentation processes and bioreactor design
Biocatalysis and enzymatic processes
Recovery and purification of small molecules
Recovery and purification of large molecules
Process economics and scale-up
Biochemical and Bioprocess Engineering

Pharmaceuticals and Fine Chemicals
Introduction from Nick Turner and Andy Wells
Industrial Example 1: Hydrolases
Industrial Example 2: Transaminase
Industrial Example 3: DERA Aldolase
Industrial Example 4: Alcohol Dehydrogenases
Industrial Example 5: Nitrile Hydratases
Industrial Example 6: Amino Acid Oxidases
CHEM21
References and Further Reading
Pharmaceuticals and Fine Chemicals

Case Studies: Bioenergy and Biomaterials
Introduction from David Leys
The challenges of sustainable bioenergy development
New routes to biofuel production
Membrane processes in industrial biotechnology
Enzymatic biofuel cells
Biomaterials: engineering cell niches hydrogels
Biomanufacturing
Reading List
Glossary
Case Studies: Bioenergy and Biomaterials

Case Studies: Glycoscience and Biotherapeutics
Introduction from Sabine Flitsch
Introduction from Alan Dickson
Introduction to glycoscience
Glycoscience: pharmaceuticals & personalised medicines
Glycoscience: other applications
Biopharmaceuticals: the clinical significance
Biopharmaceuticals: the technical stuff
Biopharmaceuticals: the industrial perspective
Glycoscience

Summary of User Reviews

Industrial Biotechnology is a highly rated course on Coursera that covers the basics of industrial biotechnology, including its applications in agriculture, food, and pharmaceutical industries. Many users appreciate the practical approach of the course that provides a clear understanding of the subject matter.

Key Aspect Users Liked About This Course

The course offers a practical approach that helps learners to understand the subject matter in a clear and concise manner.

Pros from User Reviews

The course covers a wide range of topics in industrial biotechnology.
The instructors are knowledgeable and provide clear explanations.
The course is well-structured and easy to follow.
The course offers practical examples that help learners to understand the concepts better.

Cons from User Reviews

Some learners find the course to be too basic and not challenging enough.
The quizzes could be more challenging.
The course could benefit from more interactive elements such as quizzes and assignments.
Some learners feel that the course lacks depth in certain areas.

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