Experimental Methods in Systems Biology

  • 4.5
Approx. 18 hours to complete

Course Summary

Learn the fundamentals of experimental methods in social science research, including how to design studies, collect and analyze data, and draw conclusions.

Key Learning Points

  • Gain a solid understanding of research design and data analysis techniques
  • Learn how to draw valid conclusions from data
  • Explore the ethical considerations of conducting experiments
  • Get hands-on experience designing and conducting your own experiments

Related Topics for further study


Learning Outcomes

  • Understand the principles of experimental design
  • Gain practical experience designing and conducting experiments
  • Learn how to analyze and interpret data

Prerequisites or good to have knowledge before taking this course

  • A basic understanding of statistics
  • Access to statistical analysis software, such as SPSS or R

Course Difficulty Level

Intermediate

Course Format

  • Online
  • Self-paced

Similar Courses

  • Research Methods for Data Analysis
  • Experimental Design and Analysis

Related Education Paths


Related Books

Description

Learn about the technologies underlying experimentation used in systems biology, with particular focus on RNA sequencing, mass spec-based proteomics, flow/mass cytometry and live-cell imaging.

Outline

  • Introduction
  • Lecture 1 -Scope and Overview
  • Lecture 2 - Biological Model Systems
  • Lecture 3 - Experimental Perturbations
  • Lecture 4 - Measuring Nucleic Acids
  • Lecture 5 - Measuring Protein and Protein States
  • Lecture Slides
  • Lecture Slides
  • Lecture Slide
  • Lecture Slides
  • Lecture Slides
  • Reading List
  • Quiz 1
  • Deep mRNA Sequencing
  • Lecture 1 - History of Sequencing
  • Lecture 2 - 2nd and 3rd Generation Sequencing
  • Lecture 3 - Illumina-Based mRNA Sequencing
  • Lecture 4 - Lab-Based Video
  • Lecture 5 - mRNA Sequencing Data Analysis
  • Lecture Slides
  • Lecture Slides
  • Lecture Slides
  • Reading List
  • Quiz 2
  • Mass Spectrometry-Based Proteomics
  • Lecture 1 - Basics of Mass Spectrometry 1
  • Lecture 2 - Basics of Mass Spectrometry 2
  • Lecture 3 - Quantification in Proteomics
  • Lecture 4 - Lab-Based Video - Proteomics Day 1
  • Lecture 5 - Lab-Based Video - Proteomics Day 2
  • Lecture 6 - Lab-Based Video - Analysis
  • Lecture Slides
  • Lecture Slides
  • Reading List
  • Quiz 3
  • Midterm Exam
  • Midterm Exam
  • Flow and Mass Cytometry for Single Cell Protein Levels and Cell Fate
  • Lecture 1 - Flow Cytometry 1
  • Lecture 2 - Flow Cytometry 2
  • Lecture 3 - Mass Cytometry
  • Lecture 4 - Cytometry Data Analysis
  • Lecture 5 - Lab-Based Video - Flow Cytometry - Acquisition
  • Lecture 6 - Lab-Based Video - Flow Cytometry - Analysis
  • Lecture 7 - Lab-Based Video - Mass Cytometry
  • Lecture Slides
  • Lecture Slides
  • Lecture Slides
  • Reading List
  • Quiz 4
  • Live-cell Imaging for Single Cell Protein Dynamics
  • Lecture 1 - Fluorescence Microscopy
  • Lecture 2 - Types of Imaging
  • Lecture 3 - Visualizing Molecules in Living Cells: Fluorescent Tools
  • Lecture 4 - Quantification
  • Lecture 5 - Lab-Based Video
  • Lecture Slides
  • Lecture Slides
  • Lecture Slides
  • Reading List
  • Quiz 5
  • Integrating and Interpreting Datasets with Network Models and Dynamical Models
  • Lecture 1 - Omics data and Network Model Analyses
  • Lecture 2 - Single Cell Time Course Data and Dynamical Model Analyses
  • Lecture 3 - Dynamical Model Case Study
  • Lecture Slides
  • Lecture Slides
  • Lecture Slides
  • Reading List
  • Quiz 6
  • Final Exam
  • Final Exam

Summary of User Reviews

Key Aspect Users Liked About This Course

The course is well-structured and easy to follow.

Pros from User Reviews

  • Clear explanations of concepts
  • Useful examples and exercises
  • Engaging and knowledgeable instructors

Cons from User Reviews

  • Some materials may be too basic for advanced learners
  • Lack of interaction with other students
  • No certificate of completion for free enrollment
English
Available now
Approx. 18 hours to complete
Marc Birtwistle, PhD
Icahn School of Medicine at Mount Sinai
Coursera

Instructor

Marc Birtwistle, PhD

  • 4.5 Raiting
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