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Clinical Kidney, Pancreas and Islet Transplantation

Approx. 35 hours to complete

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Course Summary

This course provides an overview of clinical kidney transplantation, including indications and contraindications for transplantation, evaluation of potential kidney transplant recipients and donors, and management of post-transplant complications.

Key Learning Points

Learn the latest advancements in clinical kidney transplantation
Understand the evaluation processes for potential kidney transplant recipients and donors
Gain knowledge on the management of post-transplant complications

Learning Outcomes

Understand the process of clinical kidney transplantation
Identify the key factors in evaluating potential kidney transplant recipients and donors
Gain knowledge on the management of post-transplant complications

Prerequisites or good to have knowledge before taking this course

Basic knowledge of biology and anatomy
Familiarity with medical terminology

Course Difficulty Level

Intermediate

Course Format

Online self-paced
Video lectures
Quizzes

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Description

Kidney transplantation is a major advance of modern medicine which provides high-quality of life for patients with end-stage renal disease. What used to be an experimental, risky, and very limited treatment option more than 50 years ago is now routinely performed in many countries worldwide. The number of renal transplants is expected to rise sharply in the next decade since the proportion of patients with end stage renal disease is increasing.

Are you interested in clinical kidney, pancreas and islet transplantation? If you are a (bio) medical student or a health care professional who works in the (pre) clinical transplant field this might be the course for you. This course is also for anyone interested in the research and knowledge on clinical transplantation. The course will be taught by a multidisciplinary team of transplant professionals and will give you the state of the art updates. It is divided in 4 modules: 1) Before the transplant 2) The surgical procedures and the challenged patient, including the patient with diabetes 3) Early challenges 4) Late challenges after transplantation. The offered modules will include lectures, interactive patient cases, 3D movies, interviews with well-known experts and with patients and a donor, a serious game to increase knowledge of the field and of course an active forum. Become an expert and join us! The course is endorsed by The European Society of Organ Transplantation (ESOT), The International Society of Nephrology (ISN) and The Transplantation Society (TTS). This MOOC has been accredited for Continuing Medical Education (CME). Health care professionals who works in the (pre) clinical transplant field, other health care professionals and general practitioners can obtain CME credit at 'LUMC-Boerhaave CME' upon passing the course. For more information we like to refer to the "Additional introduction for obtaining CME credit" module in week 1 of the course For another interesting course on organ donation and transplantation, see Organ Donation: From Death to Life from Cape Town University https://www.coursera.org/learn/organ-donation

Outline

Welcome to the course
Trailer Clinical Kidney Transplantation
How to succeed in your online class?
About us: Introduction to the Team
Leiden University: Facts & Figures
Tips for studying online
Community Guidelines
What is your learning path?
CME information
How to apply for CME credit
CME FAQs

Before the Transplant
Short Introduction
The Kidney in Health and Disease
Options if Kidneys Fail
Immunogenetics
Introduction to the Immune System
The Humoral Immune System
Histocompatibility
Cases from Daily Practice - Patient Selection
Eurotransplant Company Film 'More than a Match'
Interview: Transplant Recipient and Donor: Part 1
Epitopes
Glossary
References
HLA Epitope Matching is the Future
HLA Antibody Detection: Not All Antibodies are the Same
Check your knowledge
Check your knowledge

The Procedure and the Patient
Short Introduction
Immunological Challenged Patient: ABO Incompatible Transplants
Immunological Challenged Patient: Highly Sensitized Patient
The Diabetic Patient
The Elderly Patient
Organ Procurement and Preservation
Kidney Transplant Surgery
Simultaneous Pancreas Kidney & Islet Transplantation
A: Cases from Daily Practice: Different Choices for Different Diabetic Patients
B: Cases from Daily Practice: Different Choices for Different Diabetic Patients
Interview: Patient with Diabetes
Interview: Transplant Recipient and Donor: Part 2
B Cell Replacement and Diabetes Type II
Surgical Challenged Patients
Introduction to Watching 360 VR Videos
Serious Game: A Patient with Immunological Challenges
Glossary
References
Highly Sensitized Patients: The AM Program
Additional Challenged Transplant Recipients
Living Kidney Donation
Check your knowledge
Check your knowledge

Early Challenges in Transplantation
Introduction & Overview of Early Challenges in Transplantation
Surgical Challenges in the Early Period
Ischemia Reperfusion Injury
Cellular Rejection
Antibody Mediated Rejection
Immune Suppression
Novel Therapeutics: Cell Therapy after Transplantation
Cases from Daily Practice A - Patient Cases with Early Challenges
Cases from Daily Practice B - Patient Cases with Early Challenges
Interview Transplant Recipient & Donor: Part 3
The Complement System and Transplantation
Cases from Daily Practice: Patient Case with an Early Challenge
Serious Game: Interactive Patient Case
Optional - Immunesuppressive Regimens and Toxicity Profiles
Biomarkers
Therapeutic drug monitoring of immunosuppressive drugs
Glossary
References
A closer Look at Antibody Mediated Rejection
Innate Immunity and Impact on Transplantation
Molecular Insights into Cellular Rejection
Check your knowledge
Check your knowledge

Late Challenges in Transplantation
Introduction & Overview of Late Challenges in Transplantation
Infections: Overview and CMV infection
Infections: BK and EBV infection
Malignancies
Late Challenges after Pancreas and Islet Transplantation
Post Transplant Diabetes Mellitus
Cardiovascular Disease
Tolerance: Interview with Prof. Claas (LUMC) and Prof. Wood (Oxford)
Cases from Daily Practice A - Patient Cases with Late Challenges
Cases from Daily Practice B - Patient Cases with Late Challenges
Recurrence of Kidney Disease after Transplantation
Vaccination and Transplantation
Pneumocystis jirovecii
Glossary
References
Skin Diseases after Transplantation and Dermatological Aftercare
Tolerance in more Detail
Check your knowledge
Patient Case 1: Enhanced Glucose after SPK
Patient Case 2: Hyperglycemia after Islet Transplantation
Patient Case 3: A Complication after Pancreas-alone Transplantation
Check your knowledge

Final Quiz
Final Exam
Final Honours Exam

Summary of User Reviews

Discover the clinical aspects of kidney transplantation with Coursera. This course has received positive feedback from users for its comprehensive content and expert instructors.

Key Aspect Users Liked About This Course

Users appreciated the in-depth coverage of the subject matter, which helped them gain a better understanding of the clinical aspects of kidney transplantation.

Pros from User Reviews

Expert instructors with practical knowledge and experience
Clear and concise explanations of complex topics
Interactive quizzes and assignments for enhanced learning
High-quality video lectures with rich visuals
Flexible schedule with self-paced learning

Cons from User Reviews

Limited discussion forums and peer interaction
Some users found the course material to be too technical
No live sessions or real-time support from instructors
Some technical issues reported with the online platform
No certificate or credential offered for completing the course

languageEnglish

start dateAvailable now

durationApprox. 35 hours to complete

teacherMarlies Reinders, Frans Claas, Cees van Kooten , Sebastiaan Heidt, Volkert Huurman, Hans de Fijter, Eelco de Koning , Andre Baranski, Ton Rabelink, Aiko de Vries, Jan Nico Bouwes Bavinck, Leo Visser , Ingeborg Bajema

institutionUniversiteit Leiden, Leiden University Medical Center

course taken onCoursera

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Clinical Kidney, Pancreas and Islet Transplantation

Kidney transplantation is a major advance of modern medicine which provides high-quality of life for patients with end-stage renal disease. Are you interested in clinical kidney, pancreas and islet transplantation?...

Save Course