Bioinformatic Methods I

  • 4.7
Approx. 20 hours to complete

Course Summary

Learn about the fundamental concepts and tools used in bioinformatics, and their application in analyzing DNA, RNA, and protein sequence data.

Key Learning Points

  • Understand the basics of bioinformatics and its various applications.
  • Learn how to manipulate and analyze DNA, RNA, and protein sequence data.
  • Gain hands-on experience with bioinformatics tools and databases.

Job Positions & Salaries of people who have taken this course might have

  • Bioinformatics Analyst
    • USA: $70,000 - $110,000
    • India: ₹4,00,000 - ₹9,00,000
    • Spain: €30,000 - €50,000
  • Genomics Scientist
    • USA: $90,000 - $130,000
    • India: ₹6,00,000 - ₹12,00,000
    • Spain: €40,000 - €60,000
  • Biostatistician
    • USA: $80,000 - $120,000
    • India: ₹5,00,000 - ₹10,00,000
    • Spain: €35,000 - €55,000

Related Topics for further study


Learning Outcomes

  • Understand the principles of bioinformatics and its applications
  • Analyze DNA, RNA, and protein sequence data using bioinformatics tools
  • Gain practical skills in bioinformatics through hands-on experience

Prerequisites or good to have knowledge before taking this course

  • Basic understanding of biology and genetics
  • Familiarity with programming languages such as Python or R

Course Difficulty Level

Intermediate

Course Format

  • Online self-paced
  • Video lectures
  • Hands-on assignments
  • Quizzes and exams

Similar Courses

  • Bioinformatics: Introduction and Methods
  • Genomic Data Science
  • Introduction to Computational Thinking and Data Science

Related Education Paths


Notable People in This Field

  • Director of EMBL-EBI and a leading figure in genomics and bioinformatics
  • Professor of Mathematics and Computer Science at MIT, and a pioneer in the field of bioinformatics

Related Books

Description

Large-scale biology projects such as the sequencing of the human genome and gene expression surveys using RNA-seq, microarrays and other technologies have created a wealth of data for biologists. However, the challenge facing scientists is analyzing and even accessing these data to extract useful information pertaining to the system being studied. This course focuses on employing existing bioinformatic resources – mainly web-based programs and databases – to access the wealth of data to answer questions relevant to the average biologist, and is highly hands-on.

Outline

  • NCBI/Blast I
  • Introduction
  • Lecture
  • Lab Discussion
  • Summary
  • Acknowledgements
  • Course Logistics
  • Lecture Materials
  • Lab 1 -- Exploring NCBI
  • Lab 1 Quiz
  • Blast II/Comparative Genomics
  • Introduction
  • Lecture
  • Lab Discussion
  • Summary
  • Lecture Materials
  • Lab 2 -- Advanced Blast and Comparative Genomics
  • Lab 2 Quiz
  • Multiple Sequence Alignments
  • Introduction
  • Lecture
  • Lab Discussion
  • Summary
  • Lecture Materials
  • Lab 3 -- Multiple Sequence Alignment
  • Lab 3 Quiz
  • Review: NCBI/Blast I, Blast II/Comparative Genetics, and Multiple Sequence Alignments
  • Quiz: Modules 1-3
  • Phylogenetics
  • Introduction
  • Lecture
  • Lab Discussion
  • Summary
  • Lecture Materials
  • Lab 4 -- Phylogenetics
  • Lab 4 Quiz
  • Selection Analysis
  • Introduction
  • Lecture
  • Lab Discussion
  • Summary
  • Lecture Materials
  • Lab 5 -- Selection Analysis
  • Lab 5 Quiz
  • 'Next Gen' Sequence Analysis (RNA-Seq) / Metagenomics
  • Introduction
  • Lecture
  • Lab Discussion
  • Summary
  • Lecture Materials
  • Lab 6 -- Next Generation Sequencing Applications: RNA-Seq and Metagenomics
  • Lab 6 Quiz
  • Review: Phylogenetics, Selection Analysis, and 'Next Gen' Sequence Analysis (RNA-seq)/Metagenomics + Final Assignment
  • Final Assignment Instructions
  • Review: Modules 5-7
  • Final Assignment

Summary of User Reviews

Bioinformatics Methods 1 on Coursera is a highly rated course that covers a range of topics related to bioinformatics. Many users have praised the course for its comprehensive coverage of the subject matter.

Key Aspect Users Liked About This Course

Comprehensive coverage of bioinformatics topics

Pros from User Reviews

  • Clear and concise explanations
  • Engaging and interactive course material
  • Great support from instructors and teaching assistants
  • Practical assignments that reinforce learning
  • Excellent preparation for further study or work in the field

Cons from User Reviews

  • Some technical issues reported with the online platform
  • Course can be quite challenging for beginners
  • Limited opportunities for interaction with other students
  • Not all modules may be relevant for all learners
  • Course may require a significant time commitment
English
Available now
Approx. 20 hours to complete
Nicholas James Provart
University of Toronto
Coursera

Instructor

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